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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

一些智能的床会让你有更好的睡眠质量和睡眠姿势,但也会让你变成一个检查配偶是否出轨的私家侦探。除了检测这个床垫是否舒适,它会在有其他人占用你的床的时候提醒你。
? Aid workers are worried about a food crisis in Haiti, where Hurricane Sandy killed 52 people last week. The UN is also concerned that flooding could lead to a sharp rise in cholera cases. At least 69 people were killed by Sandy in the Caribbean.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

6. 2012年搞笑诺贝尔奖之文学奖
There are two divergent views of what is happening to the oil price ithin the industry and among serious investors. 2016 may help us to see which is correct.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 武汉:春节前 114个楼盘将入市
Open Access Perspective

Soft matter science and the COVID-19 pandemic

But with Jrue Holiday back and Anthony Davis putting up historic numbers, they aren't going to be bad enough to get a Fultz or Jackson. Why couldn't last year's draft class be this good?

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 高端改善楼盘 案场人气有所下滑
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

我发现自己经常担心一些事情

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

根据美国影院业主协会的数据显示,2015年全球影院收益达383亿美元创新高,中国贡献了68亿美元的票房收入,较上一年增长了近五成。
Comic skit “Dance If You Like” (Cai Ming and Pan Changjiang)
Lecent Ross枪击案已逮捕两人
The Great Recession had devastating effects across the U.S. and few places were as hard hit as Arizona. The state was booming on the strength of its tourism and real estate markets during the 2000s. Median home prices jumped 70% between 2003 and 2006—only Nevada had bigger gains—fueling more building and construction jobs. Monthly unemployment was at 3.5% through much of 2007. But then the bottom fell out. Home prices plummeted more than 50% from their peak and 6% Arizona properties received foreclosure filings in 2009. Unemployment stubbornly remained in double-figures for most of 2009 and 2010 and only Nevada lost a higher percentage of jobs over the last five years. Household incomes declined at the fastest rate in the country since 2008.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

那么,这对2015年的油价意味着什么呢?人们对此各执己见。然而,今后12个月的油价走势将由下列五大因素(排名不分先后)决定。
15. 《旅行终点》(The End of the Tour) ,导演:詹姆斯·庞索特(James Ponsoldt)。
7.Do not ask a policeman the best way to get to the West End or how to use an Oyster card. He wants to help, but he's from the West Midlands.
In comments reported by state news agency Xinhua on Thursday from a speech given at a meeting of regional leaders in Cambodia on Wednesday, Mr Li said the Chinese economy had performed above expectations in 2017 as trade reversed two years of declines.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

In 2007, Apple released the first iPhone: a full touchscreen phone, complete with its own virtual keypad. To many, Apple had done something new, something never seen before. They had made the first touchscreen phone. But this was incorrect: Apple did not make the first touchscreen phone, nor was the touchscreen a new invention.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The Post

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

即便亚洲国家推出了在其他国家推动ETF市场蓬勃发展的监管措施,也仍存在其他障碍。例如,蒙塔纳里表示,提供给亚洲投资者的产品大多与国内市场的股票挂钩,因此ETF没有被用来让投资者在国内投资于外国市场。
虽然她五个月之前才刚学会走路,但是这个被人们称作“宝贝碧昂斯”的小宝宝已经开始在各种盛会的舞台上展露风采了。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

4.统计学家
排名:第五

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

adj. 永久的,永恒的
据哈佛大学校报报道,至少10名学生因在脸书私聊小组中发布“猥琐表情”而失去哈佛大学的入学资格。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 发改委:统一规范特色小镇
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

outrage
年龄对詹姆斯仍不是问题
She has also performed on Jimmy Kimmel and The Ellen Show - not bad for someone who hasn't even hit adolescence.
动作、探险剧《盗墓笔记》改编自徐磊(笔名南派三叔)的畅销网络小说。它也是中国第一部季播网络剧,预计该小说将被改编为8季,每年播出一季。第一季于2015年6月播出。同名系列小说讲诉了吴邪和小伙伴们在古墓探险的故事,该小说2006年在网上发布后受到了大量粉丝的追捧。因此,大家对改编电视剧期望颇高,不过它却让粉丝们大跌眼镜。尽管首播2分钟后,网络点击量就超过了2千4百万,不过第一季的薄弱情节和粗劣品质很快就被粉丝们炮轰了。剧中的一些台词甚至成了社交媒体上调侃的段子。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 三四线城市将成橱柜企业布局方向
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

"The CPI just went up two percent year on year in 2016, less than the three-percent predictive index. It was a moderate inflation, and reflected the price level was effectively controlled and basically stable," said Jin.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

根据中国海关的数据,今年头十个月,中国对美国出口同比增长5.2%,对东盟(Asean)国家出口同比增长3.7%。
“我们从斯雷布雷尼察大屠杀事件了解了荷兰和荷兰人是什么样的,”埃尔多安说起现代荷兰历史上最可耻的一幕,“我们从他们屠杀那里的8000名波斯尼亚人就知道,他们品德败坏到何等地步。”

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Goldie Hawn’s award for best supporting actress in the 1970 film Cactus Flower rests somewhere altogether more zen – in the “India Room” in which she likes to meditate. Hers isn’t the only award to apparently emit good vibes – Russell Crowe’s award for best actor, which he won for his role as the bang-on-trend, leather miniskirt clad Maximus Decimus Meridius in Ridley Scott’s 2000 film Gladiator, is kept in a chicken coop on the actor’s Australian ranch. Crowe apparently thinks it helps the hens lay bigger eggs.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

8. Ford Motor

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Celebrity Latin tattoos may be fuelling a revival of the ancient language in schools, it emerged today。  明星们的拉丁语纹身引发了一阵学习拉丁语的热潮。
可口可乐CEO穆泰康是第一代美国移民,同时也是业界的领袖人物。他认为移民改革对企业有好处。2月份,他在《今日美国》(USA Today)的评论版对页文章中表示,他庆幸自己能够在美国生活,而且他认为其他外国创业者也应该获得同样的机会。穆泰康写道,他支持移民改革的原因是移民“是这个伟大国家进步基石的关键组成部分。我们必须让决心来到美国、同时又拥有高超技能的人更容易在这里生存和生活下去。”
The city offers excitement beyond your expectations, with grand churches, a richly varied number of museums, a growing modern-art scene and streets that come alive with summer festivals.
The best bosses understand the art of delegation. My commenter said something along the lines of, “They’ve fired themselves from their previous job,” meaning that they don’t interfere in the day-to-day and minute-to-minute workflow or processes. In essence, learning to delegate instead of micromanage is about trust。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

《权力的游戏》
Chinese industrial profits slumped by a record 8 per cent last month, as Beijing’s targeted stimulus efforts failed to arrest a slowdown in the key driver of China’s economy.
Lian Ping, chief economist with the Bank of Communications, said rising producer prices may push up consumer prices in the longer term.
由于预算充足,该公司的部门经理们可以用独一无二的个性化方式来奖励自己的下属。以下是两个曾给出的奖励:免费在马术训练场驰骋、附带套索和马术表演课程的烤肉野餐。
继续开放

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

5. Gross warns: 'Ponzi Scheme! Tipping Point! Credit Supernova!'
夏奇拉

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

PRICE PER SQUARE FOOT: $310

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

《日落》

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

传统上,在教学和研究水平方面,中国大学在国际排名排行榜上的评价要比美国和欧洲的高校逊色一些。
But nearly two-thirds (65 percent) of white evangelical Protestants say they think the storms are evidence of the "end times" as predicted by the Bible.
Among the year’s biggest surprises was the plunge in gasoline pries. Economists differed on the economic impact—money in the pockets of consumers offset by declines in exploration and drilling activity—but everyone agreed that it was bearish for small cars and hybrids. The combination of cheap gas and a steep sticker price made the Cadillac ELR the runaway winner of the most disliked car of the year award. Only 155 of the Volt-based $80,000 cars found buyers in November.
Lucy Kay 成为亚军,而正太组合 Bars and Melody 位列第三。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

阿里巴巴旗下品牌淘宝位居第二,品牌价值429亿美元,超过了中国移动、百度和中国工商银行。
《自己土地上的陌生人: 美国右翼的愤怒与哀悼》(Strangers in Their Own Land: Anger and Mourning on the American Right)一书的作者阿莉?罗素?霍克希尔德(Arlie Russell Hochschild)对路易斯安那州的农村社区进行了四年的研究,她认为那里“深藏着”一种失去机会的感觉。
此外,规模以上工业增加值的同比增长,是在同期出口下滑7.3%的背景下取得的。
自动驾驶汽车,自拍杆,无人驾驶飞机,触屏设备,电子香烟,喷射背包和许多其他看起来像现代的发明的东西,其实都是老发明。大部分的"发明者"把它们当做新发明,甚至去申请专利。但事实是,这些"发明"已经存在一段时间了。它们都有早期类似的原型,这些早期产品最终没有投入生产,或因为特定原因而限量生产。而有些"发明"得以大批量生产,却因为销售不佳而流产。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

2010年英文新年祝福邮件
An EMBA also boosts corporate careers. “The skills I acquired were key to my promotion,” said one graduate. A fifth are now chief executives, managing directors or board members three years after graduation. Average salaries were up 52 per cent from $114,000 before the programme to $175,000 five years later.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Maybe not a supernova player, but a good one who could get them right back on solid footing more quickly than these other teams we're discussing. Play out the season, pay off your debt, and move forward without that hanging over your head.
n. 能力,容量,容积; 资格,职位
Purchase products like magazine racks, shelves, and desk organizers that will keep your supplies and resources in order and close-at-hand. We love the File File, $24.95, at CB2.com (pictured above).
8.触感人造手
如果这个目标真的能够实现,届时特斯拉的规模将超过林肯(Lincoln)和保时捷(Porsche)等豪车品牌的美国分支。这两个老字号豪车品牌都有更多样化的产品阵容、长期的经销商网络、成熟的营销和广告策略。特斯拉如果真的能卖出预期的数字,那么其销量的半数将来自现有的Model S轿车,其它一半则来自明年年初才会量产的Model X七座跨界车。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Total net profit for China’s commercial banks grew by 2.4 per cent last year, according to data from China’s bank regulator. Smaller banks saw increases in profit growth, while bigger banks slowed down.
然而,主要榜单上的排名大幅上升不会自动转化为欧洲商学院排名的上升。例如,牛津大学(University of Oxford)萨伊德商学院(SaBusiness School)在MBA榜单上的排名上升1位,在开放招生EMBA课程的排名上升5位,在EMBA榜单上的排名上升12名,首次进入该榜单前十名,但其在欧洲商学院榜单上的排名没有变化,依然是第10名。
My bet is those forces — and America’s CEOs — will continue to temper the president’s trade tantrums in the short term. But there are lots of people baying for Chinese trade blood in Washington these days.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

本地社交媒体广告,即那些恰好出现在你的Twitter和Facebook信息流之中的广告,在2013年爆炸式增长。2014年,无论你爱也好,恨也罢,这类广告的规模只会变得越来越大。,尽管听起来有点让人毛骨悚然,但特定位置定位技术预计将在来年出现显著改进。Twitter刚刚推出了一项面向特定邮政编码区域发送有偿消息的功能。比如,当你走进一个社区,当地酒吧、干洗店和麦当劳(McDonald's)发布的“推广消息”就会突然闪现在你的Twitter信息流之中。自2011年来,Facebook一直在采用这种“地理围栏”技术。它能够让商家招揽临近的客户,这些客户实际上可能也想获得提供特别优惠和特价商品的广告信息。好处是,你可以获得更多相关的广告和推销信息。缺点同样是,更多的广告。
The total number of qualified applicants reached 31,220 in the first 24 hours, up from 25,000 over the same period last year, according to figures from offcn.com, an education organization that offers training for the civil servant exam.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

OUTDOOR SPACE: Steps down from the patio is a walled garden with a lawn and a fountain. The property is 0.10 acre.
将第1题到第9题的分数相加,计算自己在“消极情感”维度的得分。
1.水上类比赛项目

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

We will develop cultural programs and industries.
在007电影主题曲榜单上,《女王密使》的主题曲获得荣誉推荐。
这些新数据是由一个叫做全球碳计划(Global Carbon Project)的追踪项目提交的,发表在了期刊《自然·地球科学》(Nature Geoscience)上。数据公布之际,正是联合国(United Nations)一次峰会召开前夕。此次峰会意在激发新的政治愿望来解决气候变化问题。科学家说,这些数据表明,如果要把长期的全球变暖问题控制在可以承受的范围内,还需要做出极大的努力。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

More advanced components are in short supply, however, which could leave many customers waiting long after September to get hold of the new iPhone. That presents an opportunity for rivals such as Samsung’s new Note 8 or Essential, the smartphone maker led by Android co-founder Andy Rubin, which is targeting premium customers such as Apple’s with its slick $699 device. Google is also said to be preparing a new version of its Pixel smartphone, which has proved popular with early adopters.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

根据2016年胡润百富榜,中国房地产大亨王健林击败了阿里巴巴集团创始人马云以及异军突起的宝能投资集团董事长姚振华,再度蝉联中国首富。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

The projects will also cover infrastructure programs such as new connections between Tongzhou and downtown Beijing, sewage and waste water disposal, and energy facilities. Cultural projects will be carried out to provide more employment opportunities, as the construction proceeds on a Universal Studios theme park and a training facility for the National Center for Performing Arts, Lu said.
Once you grow your hair slightly longish, be sure to play with it at every opportunity.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

紧随Fitbit和谷歌眼镜(Google Glass)之后,许多公司开始蜂拥进入这一市场,带来了许多装有感应器的臂章、服饰以及眼镜。这个领域现在炙手可热,但最早使用这些设备的人们似乎都在等待那个时刻,让他们不再显得特立独行。(你知道的,谷歌眼镜的粉丝们现在有了个专门的贬义称呼“Glasshole”。)
The top obsession of 2010 was the much-anticipated iPhone, followed by actress Lindsay Lohan, the iPad, and the television shows "Glee" and "Jersey Shore".
昨天,中国一次控制爆破让19栋楼在10秒钟之内被夷平。
徐成光在新闻发布会上表示,截至上午10时20分,已打捞出97具遗体。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Until now, testing reliably for lead was expensive and meant sending away samples for analysis.
7. AT&T

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Despite being the most heavily nominated stars of the evening, Taylor - who did not attend the event - was overshadowed by 19-year-old singer Shawn who cleaned up at the awards show.
Stand: Starbucks CEO Howard Schultz urged the end of government shutdown

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

英国剑桥大学(University of Cambridge)佳奇商学院(Judge Business School)的排名上升5个位次,至第5位。这不仅是该学院首次跻身前5名,而且还是伦敦商学院在这个榜单上首次失去英国最佳商学院这个头衔。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 个税起征点提至5000元有望10月实现
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

A panel of eight WardsAuto editors evaluated 44 engines among all vehicle types during October and November in the course of their daily commutes and weekend activities in and around the Detroit metro area. Engines were rated according to a wide range of characteristics including horsepower and torque, fuel economy, noise, vibration and harshness characteristics, technology and how they fared against competing powerplants.
体操、蹦床、竞技体操、艺术体操、
Millions of people working or studying out of their hometowns will be hurrying home to reunite with families as the Chinese Spring Festival approaches. This long-held tradition is the main reason for the rush. The other is that the holiday is one of the two week-long holidays of the year, a perfect travel time for many people. The rush usually begins 15 days ahead of the Chinese Lunar New Year and 25 days after that.
In a sign that civil service jobs may be losing their appeal, a report issued by recruitment website Zhaopin in late March said more than 10,000 public sector employees, including civil servants and staff members at public institutions, had submitted their resumes to potential employers through the site in just two months. The number was 34 percent higher during the same period last year, the report said.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Effective bosses must be effective decision makers. He or she cannot vacillate over every tiny decision. Being able to make decisions quickly and decisively — and then take responsibility for the outcome (see number 2) — is an important business skill, especially when managing others。
在Teach First当老师能够不受此类条件束缚,体现了该项目的优势——该机构不仅是英国私营部门招聘企业的竞争对手,也成了它们的一所精修学校。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

It has now entered the top 20 for the first time.
The first wearable computer glasses were made by Edward Thorp and Claude Shannon in 1961. In 1968, Ivan Sutherland made the "Sword of Damocles." It was the first head-mounted computer display and an early variant of all wearable computer glasses we have today. In 1980, Steve Mann, known today as the father of wearable computing, made the "WearComp", a pair of tech-enhanced glasses that was capable of communicating wirelessly with other computers and could share videos. He continued to work on the glasses over the years, and by 1999, he had come up with a pair of glasses that looked like Google Glass, or rather, that Google Glass looks like. He called it the "EyeTap."
郭晶晶与霍启刚(香港近代富豪霍英东的孙子)的秘密恋情已经引起了全民的想象,人们似乎在关注运动员赛场表现之余,也愈加关心起他们的私人生活了。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Since the establishment of Avic 1 and Avic 2 in 1999, which really marked the beginning of China’s push into the commercial aerospace market, there has been no doubt about China’s intent and the direction it wants its industry to take. But the pace at which it would achieve this ambition was less uncertain. Almost 20 years on, things have become much more clear, and there is now little doubt that China is well on its way to succeeding where several other countries have failed in becoming a full-fledged player in the large commercial aircraft manufacturing sector, with the potential to disrupt the long-standing duopoly of Airbus and Boeing.
中国一群现代汽车经销商要求韩国现代汽车赔偿8-9亿元(1.2-1.35亿美元),称现代汽车削减了向他们出口的车型,导致经销商亏损严重。
在假日期间飞行要采取特殊的策略。这也意味着人们要为重大天气延误做好准备,尤其是美国东北部和中西部的恶劣天气。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

虽然这个心脏太虚弱,不能真的输送血液,但是这种细胞组织在修复受伤的心脏肌肉方面具有巨大潜力。
We are now in the midst of the most peaceful era of human history. Back in the 1940s, 300 out of every 100,000 people would die as a direct result of war. We’re happy to tell you that that figure is now less than 1.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: “四低”态势仍将被延续
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 揭露LED灯具“同款不同价”的内幕
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

美国公司高管的薪酬不断上升,收入差距越拉越大。在这种情况下,看到一位不光关心自身收入的CEO不禁让人眼前一亮。9月份,联想首席执行官杨元庆宣布,他将连续第二年和大约1万名联想员工分享他的奖金,数额至少为300万美元。他做出这个慷慨决定的原因是这家个人电脑制造商的年度销售额创下了历史新高。据彭博新闻(Bloomberg News)报道,参与“分成”的联想员工获得的奖金大约相当于中国普通城镇就业者一个月的收入。
目前还不清楚拉格菲尔德离世之后将由谁来照顾邱佩特。
新上榜人物:今年15位新上榜女性包括:韩国总统朴槿惠(排名第11);洛克希德·马丁公司首席执行官玛丽莲·休森(排名第34);首席执行官托里·伯奇(排名第69);Spanx创始人萨拉·布雷克里(排名第90)和百度首席财务官李昕晢(排名第98)。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Consider:
2. Get a Belstaff coat and blue scarf. The coat cost about 1350 pounds. It's got good twirl for those dramatic moments in life.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.
几家与韩国有关系的机构已经感受到了北京方面对萨德计划的怒火。上个月,由于乐天(Lotte)出让土地用于部署萨德平台,中国官方新闻机构新华社(Xinhua)向乐天发出了强硬警告。乐天是韩国最大的企业之一。
本周四公布的一项最新调查显示,近四成美国居民表示,最近发生的桑迪飓风等自然灾害的严重性正是世界末日即将到来的证据,就像《圣经》中预言的那样。而超过六成的受访者认为这是气候变化所致。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

交通运输部新闻发言人徐成光通报称,未发现更多生命迹象,搜寻到生还者的希望"非常渺茫"。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
From the themed collection: 新疆五城市开展住房租赁市场试点
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Give Me Space
“我是一个医生。说实话,一个人的健康首先与吃、喝与空气有关,如果这三样不好,再提什么样的发展都没有用!”

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

With the momentum now back behind the iPhone and anticipation growing for the Watch, Mr Cook seems to have won back the confidence of Apple employees, something that analysts say was obvious in his demeanour at this year’s product launches.
立场:呼吁进行移民改革

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The list has four British universities, which are Cambridge, Oxford and London's University College and Imperial College. The University of Tokyo is also included in top 20.
干得漂亮!在不到20个词的一句话里,eBay集前五届冠军之长,做到了啥也没说。怀着沉重的心情,我将2016年度金废话奖总冠军授予eBay。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Opposition is legitimate, opinion free and power curbed.
The album is a refreshingly fun pop gem that traverses New Wave, electro-disco and dance-pop.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

私人侦探已进行指控,但是他们表示,不会公布枪击详情,除非两名年轻人周五出庭。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

瑞茜·威瑟斯彭(Reese Witherspoon)刚出道时大胆尝试不同戏路的演出,据报道,她曾努力将因影片《一往直前》(Walk the Line)获得的最佳女主角的奖杯制成门环或项链。但这两种方案都没能得以实现,现在,小金人就站在她的客厅里。
5. bedazzled / a . 眼花缭乱的。
通用汽车(GM)咸鱼翻身不易,2010年举行首次公开募股一事就别惦记了。
[r?b]

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

2.SpaceX demonstrates a big step towards fully reusable space craft

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Asia and Australia account for 11 of the world's top 20 most expensive cities, with eight from Europe and one from South America, the Economist Intelligence Unit's (EIU) worldwide cost of living index found. No North American cities featured in the top 20.
Feng said that the Goal for 2017 is to maintain an overall punctuality rate of about 75%.
该新规还专门针对出租车服务作出规定。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

portion
我是否玩儿得太high了?缺乏实现某些事情的动机会让你失去平衡或者稍后会让你感到筋疲力尽,很有压力。休息一下是非常有必要的,但是如果你休息得过了头从而使生产力降低,或者你养成了太过拖拉的习惯,那么或许就需要时间来平衡你的时间安排,以便你可以完成大量的事情而仍有时间休息娱乐。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 北京小升初明年将取消特长生招生
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

But shipments to other destinations fared far worse, particularly those to re-exporter Hong Kong, which saw the dollar value of exports from China contract 26.3 per cent year on year to $33.84bn. Shipments to EU countries also fell 4.7 per cent to $33.5bn, while those to Japan dropped 5.5 per cent to $11.27bn.
Leaders of large companies such as Michelin, Microsoft, Ericsson and others are already pushing more decision-making power out to their front-line workers. Others will follow as the success of this approach catches on.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

杜阿·里帕《杜阿·里帕》

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

中国国家统计局数据显示,10月份,食品价格的再次放缓拉低了中国的通胀率。
Last but by no means least is our favourite fact that Norway once knighted a penguin. His name is Nils Olav, and he is a king penguin who now resides on Edinburgh Zoo, Scotland. He is the mascot and Colonel-in-Chief of the Norwegian Royal Guard. He was knighted on 15th August, 2008, which was approved by King Harald V, who stated during the ceremony that Nils was "in every way qualified to receive the honour and dignity of knighthood".
At least one model of the next iPhone is expected to feature image-capture technology that can sense depth, and track faces and expressions. A range of new emojis include monkeys and robots, whose animated expressions can mirror the iPhone user’s face as Apple battles for users’ attention with the likes of Facebook and Snapchat.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

ac+cur关心+ate→一再关心,弄精确为止→准确的,精确的
当时的杜兰特身高6尺9寸,体重只有185磅,我很惊讶在高中赛打到一半时他没有被撞坏。幸运的是,杜兰特不靠在大前锋位置上力量抗衡赚钱,他主要依赖他拿手的急停跳投。
根据国内领先的求职平台前程无忧近日发布的一份关于2016年应届毕业生的研究报告显示,52.11%的高校毕业生已找到工作或自主创业。
[k?ud]

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Video editors likely benefited from the same factors that caused the increase in photography jobs. It stands to reason that this kind of work expands alongside the need for increasingly sophisticated and appealing website designs.
12岁女孩发现古埃及护符

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 辽宁:鼓励老年人自主创业
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

组建或加入一个学习小组
But this has begun to feel less like a relevant statement about what women want now and more like a retreat; an assumption, which I would characterize as false, that the past is a safe place to dress.
耶路撒冷小女孩参加“圣殿山筛选项目”考古活动时,发现一古埃及护符。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 抢人才,名企承诺可“分房”
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About this collection

根据《每日经济新闻》报道,1980版的猴年生肖纪念邮票价格由于种种原因创下了历史新高。
Entertainer of the year: Luke Bryan

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